How to Pick Up a Woman
Make eye contact. You've already established that she is available, so keep telling yourself that. This next step is key. If she looks at you and you look away nervously, good luck to you. You've already made a bad first impression. Keep a relaxed, flirtatious gaze. Don't stare and don't lock up and look like a psycho. Also don't flash a huge, fake grin. Just move your head however feels natural and smile a bit--whatever feels natural. If she looks away shyly, that's good. If she gives you a seductive stare, that's even better. If she looks away and looks freaked out, better find someone else.
Look away for a second or two to give her time to think about you. She has noticed that you're available and that you like her. She's thinking about whether she likes you back. Don't take too long. Between ten seconds and a minute. Whatever feels right. Take a deep breath, relax, think happy thoughts. She was intrigued by you, remember?
Clear your mind. Breathe. That oxygen is going to help you think on your toes and help you relax. Gulp it down politely. She may wonder if you are a fish otherwise.
Glance over at her again. If she's chatting with her friends and still has her eye on you, congratulations. If she's looking at you comfortably, congratulations. If she purposely avoids eye contact, she either has myopia or she just hasn't felt the spark her end. Approach somebody else or offer to put her glasses back on.
Keep eye contact as you approach. Don't stare and don't trip over anything as you walk toward her. Stay relaxed and focused. Have a sense of purpose. Don't let all the people who are in your way discourage you. Remember, we have already established that she likes you. If you blow it now, it's all your fault. Although, never underestimate the endearing quality of a guy who trips over in pursuit of love. It can be retold for years afterwards and who knows, it may just end in marriage.
Smile casually and say something casual. Remember, you are a stranger. There is no need to say something elaborate but at least form the words clearly - don't mumble or spit in anticipation. Here are some ideas:
"How's it going?"
"Hey what's up?"
Regardless of what her response is, ask a question next. The purpose of this question is to get her to laugh. Say something benign or even daft:
"What are you up to?" This one is a favorite. If she says "nothing," try one of the others, but if she wants to play along she'll say "dancing" * cue laugh* or "drinking" * cue laugh*
"What's your name?"
"Where's your boyfriend?" This is a good question to ask if she's been talking to a guy that she's obviously not interested in. Do you see the pattern? Humor!
Or even "What's your sign?" She just may crack up
If you are talented enough to think up your own humorous question that fits the scenario better, go for it. But please, if you don't have a rapacious wit, stick to the suggestions above.
Get on with it. You're on your own, so have a decent conversation. If you're not good at it, you will never get a pickup (unless you look like a model). Most guys can't get past the above part, so you already have a head start. Remember, if you fail at this point, it's all your fault. She doesn't really have a boyfriend and she isn't really that busy. You just didn't impress her with your conversation, that's all. Get better and try again.